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Kulkarni, A

BCS is caused by having two pathogenic variants in these genes: ZNF469 PRDM5 Cardiac-Valvular EDS (cvEDS) If a person meets the diagnostic criteria for cvEDS, genetic testing should be done to confirm the diagnosis

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It takes place primarily in liver cells, the liver being the bodys principal site of glutathione production and export

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5 Paxillin, a focal adhesion scaffolding protein that binds directly to FAK and mediates cytoskeletal remodeling, is phosphorylated in BPC-157-treated endothelial cells in a pattern consistent with enhanced migratory phenotype precisely the phenotype required for endothelial cells to form new capillary tubes during angiogenesis